Healthcare Ai持有增加患者安全性，增强效率和改善患者结果的潜力，但研究通常受到数据访问，队列策划和分析工具的限制。电子健康记录数据，实时数据和实时高分辨率设备数据的集合和翻译可能是具有挑战性和耗时的。现实世界AI工具的发展需要克服数据采集，稀缺医院资源和数据治疗需求的挑战。这些瓶颈可能导致资源沉重的需求和AI系统的研究和开发延迟。我们提供了一种系统和方法，可加速数据采集，数据集开发和分析和AI模型开发。我们创建了一个依赖于可扩展的微服务后端的交互式平台。该系统可以每小时摄取15,000名患者记录，其中每个记录代表数千个多式数级测量，文本备注和高分辨率数据。统称，这些记录可以接近数据的数据。该系统可以在2-5分钟内进一步执行队列和初步数据集分析。因此，多个用户可以在实时同时协作以迭代数据集和模型。我们预计这种方法将推动现实世界的AI模型开发，并且在长期运行中，有意义地改善医疗保健交付。

Deep neural networks (DNNs) are often used for text classification tasks as they usually achieve high levels of accuracy. However, DNNs can be computationally intensive with billions of parameters and large amounts of labeled data, which can make them expensive to use, to optimize and to transfer to out-of-distribution (OOD) cases in practice. In this paper, we propose a non-parametric alternative to DNNs that's easy, light-weight and universal in text classification: a combination of a simple compressor like gzip with a $k$-nearest-neighbor classifier. Without any training, pre-training or fine-tuning, our method achieves results that are competitive with non-pretrained deep learning methods on six in-distributed datasets. It even outperforms BERT on all five OOD datasets, including four low-resource languages. Our method also performs particularly well in few-shot settings where labeled data are too scarce for DNNs to achieve a satisfying accuracy.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Classical methods for acoustic scene mapping require the estimation of time difference of arrival (TDOA) between microphones. Unfortunately, TDOA estimation is very sensitive to reverberation and additive noise. We introduce an unsupervised data-driven approach that exploits the natural structure of the data. Our method builds upon local conformal autoencoders (LOCA) - an offline deep learning scheme for learning standardized data coordinates from measurements. Our experimental setup includes a microphone array that measures the transmitted sound source at multiple locations across the acoustic enclosure. We demonstrate that LOCA learns a representation that is isometric to the spatial locations of the microphones. The performance of our method is evaluated using a series of realistic simulations and compared with other dimensionality-reduction schemes. We further assess the influence of reverberation on the results of LOCA and show that it demonstrates considerable robustness.

As various city agencies and mobility operators navigate toward innovative mobility solutions, there is a need for strategic flexibility in well-timed investment decisions in the design and timing of mobility service regions, i.e. cast as "real options" (RO). This problem becomes increasingly challenging with multiple interacting RO in such investments. We propose a scalable machine learning based RO framework for multi-period sequential service region design & timing problem for mobility-on-demand services, framed as a Markov decision process with non-stationary stochastic variables. A value function approximation policy from literature uses multi-option least squares Monte Carlo simulation to get a policy value for a set of interdependent investment decisions as deferral options (CR policy). The goal is to determine the optimal selection and timing of a set of zones to include in a service region. However, prior work required explicit enumeration of all possible sequences of investments. To address the combinatorial complexity of such enumeration, we propose a new variant "deep" RO policy using an efficient recurrent neural network (RNN) based ML method (CR-RNN policy) to sample sequences to forego the need for enumeration, making network design & timing policy tractable for large scale implementation. Experiments on multiple service region scenarios in New York City (NYC) shows the proposed policy substantially reduces the overall computational cost (time reduction for RO evaluation of > 90% of total investment sequences is achieved), with zero to near-zero gap compared to the benchmark. A case study of sequential service region design for expansion of MoD services in Brooklyn, NYC show that using the CR-RNN policy to determine optimal RO investment strategy yields a similar performance (0.5% within CR policy value) with significantly reduced computation time (about 5.4 times faster).

Software Defect Prediction aims at predicting which software modules are the most probable to contain defects. The idea behind this approach is to save time during the development process by helping find bugs early. Defect Prediction models are based on historical data. Specifically, one can use data collected from past software distributions, or Versions, of the same target application under analysis. Defect Prediction based on past versions is called Cross Version Defect Prediction (CVDP). Traditionally, Static Code Metrics are used to predict defects. In this work, we use the Class Dependency Network (CDN) as another predictor for defects, combined with static code metrics. CDN data contains structural information about the target application being analyzed. Usually, CDN data is analyzed using different handcrafted network measures, like Social Network metrics. Our approach uses network embedding techniques to leverage CDN information without having to build the metrics manually. In order to use the embeddings between versions, we incorporate different embedding alignment techniques. To evaluate our approach, we performed experiments on 24 software release pairs and compared it against several benchmark methods. In these experiments, we analyzed the performance of two different graph embedding techniques, three anchor selection approaches, and two alignment techniques. We also built a meta-model based on two different embeddings and achieved a statistically significant improvement in AUC of 4.7% (p < 0.002) over the baseline method.

Springs are efficient in storing and returning elastic potential energy but are unable to hold the energy they store in the absence of an external load. Lockable springs use clutches to hold elastic potential energy in the absence of an external load but have not yet been widely adopted in applications, partly because clutches introduce design complexity, reduce energy efficiency, and typically do not afford high-fidelity control over the energy stored by the spring. Here, we present the design of a novel lockable compression spring that uses a small capstan clutch to passively lock a mechanical spring. The capstan clutch can lock up to 1000 N force at any arbitrary deflection, unlock the spring in less than 10 ms with a control force less than 1 % of the maximal spring force, and provide an 80 % energy storage and return efficiency (comparable to a highly efficient electric motor operated at constant nominal speed). By retaining the form factor of a regular spring while providing high-fidelity locking capability even under large spring forces, the proposed design could facilitate the development of energy-efficient spring-based actuators and robots.

Unmanned aerial vehicles (UAVs) mobility enables flexible and customized federated learning (FL) at the network edge. However, the underlying uncertainties in the aerial-terrestrial wireless channel may lead to a biased FL model. In particular, the distribution of the global model and the aggregation of the local updates within the FL learning rounds at the UAVs are governed by the reliability of the wireless channel. This creates an undesirable bias towards the training data of ground devices with better channel conditions, and vice versa. This paper characterizes the global bias problem of aerial FL in large-scale UAV networks. To this end, the paper proposes a channel-aware distribution and aggregation scheme to enforce equal contribution from all devices in the FL training as a means to resolve the global bias problem. We demonstrate the convergence of the proposed method by experimenting with the MNIST dataset and show its superiority compared to existing methods. The obtained results enable system parameter tuning to relieve the impact of the aerial channel deficiency on the FL convergence rate.

State space models (SSMs) have demonstrated state-of-the-art sequence modeling performance in some modalities, but underperform attention in language modeling. Moreover, despite scaling nearly linearly in sequence length instead of quadratically, SSMs are still slower than Transformers due to poor hardware utilization. In this paper, we make progress on understanding the expressivity gap between SSMs and attention in language modeling, and on reducing the hardware barrier between SSMs and attention. First, we use synthetic language modeling tasks to understand the gap between SSMs and attention. We find that existing SSMs struggle with two capabilities: recalling earlier tokens in the sequence and comparing tokens across the sequence. To understand the impact on language modeling, we propose a new SSM layer, H3, that is explicitly designed for these abilities. H3 matches attention on the synthetic languages and comes within 0.4 PPL of Transformers on OpenWebText. Furthermore, a hybrid 125M-parameter H3-attention model that retains two attention layers surprisingly outperforms Transformers on OpenWebText by 1.0 PPL. Next, to improve the efficiency of training SSMs on modern hardware, we propose FlashConv. FlashConv uses a fused block FFT algorithm to improve efficiency on sequences up to 8K, and introduces a novel state passing algorithm that exploits the recurrent properties of SSMs to scale to longer sequences. FlashConv yields 2$\times$ speedup on the long-range arena benchmark and allows hybrid language models to generate text 1.6$\times$ faster than Transformers. Using FlashConv, we scale hybrid H3-attention language models up to 1.3B parameters on the Pile and find promising initial results, achieving lower perplexity than Transformers and outperforming Transformers in zero- and few-shot learning on a majority of tasks in the SuperGLUE benchmark.

A "heart attack" or myocardial infarction (MI), occurs when an artery supplying blood to the heart is abruptly occluded. The "gold standard" method for imaging MI is Cardiovascular Magnetic Resonance Imaging (MRI), with intravenously administered gadolinium-based contrast (late gadolinium enhancement). However, no "gold standard" fully automated method for the quantification of MI exists. In this work, we propose an end-to-end fully automatic system (MyI-Net) for the detection and quantification of MI in MRI images. This has the potential to reduce the uncertainty due to the technical variability across labs and inherent problems of the data and labels. Our system consists of four processing stages designed to maintain the flow of information across scales. First, features from raw MRI images are generated using feature extractors built on ResNet and MoblieNet architectures. This is followed by the Atrous Spatial Pyramid Pooling (ASPP) to produce spatial information at different scales to preserve more image context. High-level features from ASPP and initial low-level features are concatenated at the third stage and then passed to the fourth stage where spatial information is recovered via up-sampling to produce final image segmentation output into: i) background, ii) heart muscle, iii) blood and iv) scar areas. New models were compared with state-of-art models and manual quantification. Our models showed favorable performance in global segmentation and scar tissue detection relative to state-of-the-art work, including a four-fold better performance in matching scar pixels to contours produced by clinicians.